Antidote Stocking Guidelines - Royal College of Emergency Medicine 2022
Royal College of Emergency Medicine and National Poisons Information Service
Introduction
⚠ Warning: this guidelines are designed specifically to be implemented within the United Kingdom.
TOXBASE (2) and/or the British National Formulary (BNF)(3) should be consulted for further advice on doses and indications for antidote administration and, if necessary, the National Poisons Information Service (NPIS) should be telephoned for more patient-specific advice. (1).
Contact details for NPIS are available on TOXBASE. Additional drugs that are used in the poisoned patient that are widely available in ED are not listed in the table – in particular it is important to ensure that insulin, benzodiazepines (diazepam and/or lorazepam), glyceryl trinitrate or isosorbide dinitrate and magnesium are immediately available in the ED. (1).
To access antidotes and other treatments (countermeasures) held nationally for the management of Major Incidents and/or CBRN Incidents please follow local Trust protocols and national guidance available on TOXBASE. (1).
Category A - Immediately Available in ED
Category B - Available within 1 hour
Category C - Held Supra-Regionally
⚠ Warning: The RCEM recommends this category of antidotes to be available within specialist sites for supply within the United Kingdom.
References
Royal College of Emergency Medicine and National Poisons Information Service Guideline on Antidote Availability for Emergency Departments (Version 6, December 2022). Accessed March 3, 2023.
RCEM (Open Access)TOXBASE. National Poisons Information Service, Scottish Poisons Information Bureau, Royal Infirmary of Edinburgh, Commissioned by the UK Health Security Service (HSA). Accessed March 3, 2023.
TOXBASEBritish National Formulary. Accredited by theThe National Institute for Health and Care Excellence (NICE, United Kingdom). Accessed March 3, 2023.
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