Procedural Sedation and Analgesia

V EN1.2.1. April 15, 2023

Introduction (1)

Preparing for Sedation and Analgesia (1)

Effective procedural sedation requires

Levels of Sedation and Analgesia (1)

Sedation exists on a continuum, and is difficult to divide into discrete clinical stages. Many sedatives can cause rapid changes in the depth of sedation. Dissociative sedation is considered to be separate from the continuum of sedation.

Adults - Pharmacological Agents for Procedural Sedation and Analgesia (1)

Pediatrics -  Pharmacological Agents for Procedural Sedation and Analgesia (1)

*reduce dose significantly in patients who are debilitated or have decreased cardiac function
** This is British National Formulary (BNF) dosing regime, many sources suggest higher dose range of 0.05-0.1mg/kg required
*** See RCEM Ketamine Procedural Sedation for Children in EDs (Feb 2020)

Related Drugs and additional suggested reading

Related drugs:

Additional suggested reading


® 2023 EMDrugs. All rights reserved.


This website provides general information and discussion about medications, health, and related subjects. The words and other con­tent pro­vided in this website, and in any linked mate­ri­als, are not intended and should not be con­strued as med­ical advice. If the reader or any other per­son has a med­ical con­cern, he or she should con­sult with an appropriately-licensed physi­cian or other legally accredited health care worker in the country that resides or is visiting. 


Please do not delay your medical concerns and potential health emergencies by searching information in this website, instead look out for medical opinion in the services that exist with that specific purpose and work under the respective local health-care regulations. 


The views expressed on this blog and web­site have no rela­tion to those of any academic, hospital, practice or other insti­tu­tion with which the authors are  affiliated. 


For other instances, the authors of this website do not have any conflict of interest with any institution or pharmaceutical company in particular, and do not receive any compensation about any licenced drug mentioned in the website. In the same matter, the website is not intended to recommend any specific patented medication.

EMDrugs Team