May 26, 2023

Practice Guidance Overview


Definition (2)

Pathophysiology (1)

GINA 2022 - Management of asthma exacerbations in the emergency department (adults, adolescents, children 6–11 years)(2)

Assessment (2)


A brief history and physical examination should be conducted concurrently with the prompt initiation of therapy. Include:

Physical examination

The physical examination should assess:

Objective assessments

GINA 2022 - Treatment in acute care settings part 1: oxygen, beta2-agonists, epinephrine and corticosteroids (2)

The following treatments are usually administered concurrently to achieve rapid improvement:

GINA 2022 - Treatment in acute care settings part 2: other treatments. Anticholinergics, aminophylline and theophylline, magnesium, helium, etc. (2)

GINA 2022 - Algorithm for Acute Asthma Exacerbation Management (2)

ICS: inhaled corticosteroids; ICU: intensive care unit; IV: intravenous; O2: oxygen; PEF: peak expiratory flow; FEV1: forced expiratory volume in 1 sec.

ACEP 2023 - Pharmacologic treatment of asthma exacerbation in the ED from the ACEP 2023 Patient Care Recommendations (adults)(3)

Algorithm Summary of Standard Pharmacotherapy within the First Hour

ACEP 2023 - Pharmacologic treatment of asthma exacerbation in the ED

Summary of Standard Pharmacotherapy: The First Hour in the ED


Beta Agonists





Other agents

Related drugs

Recommended resources about the crashing asthmatic in emergency medicine 


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