(Updated November 2022)
Rabies is a zoonotic disease positioned as one of the most lethal viral infections; mortality approaches 100%. It is also preventable in nearly 100% of expositions when vaccination (+/- rabies immunoglobulin) has been properly administered.
Vaccination and Immunoglobulin
Adult and Pediatric dose
Renal, hepatic, or other adjustments
Pregnancy and Lactation
Pregnancy: US-FDA Category C (no studies have been done in animals, and no well-controlled studies have been done in pregnant women. Rabies vaccine should be given to a pregnant woman only if potential benefits outweigh potential risks).
Pregnancy is not considered a contraindication to postexposure prophylaxis (3, 7).