Emergency Medicine Executive Summary
(Updated November 2022)
Ciclobenzaprine is a centrally acting skeletal muscle relaxant widely prescribed to relieve acute painful musculoskeletal conditions as an adjunct treatment to physical therapy and rest. It is also used as a temporary adjuvant medication along with non-steroidal anti-inflammatory drugs (NSAIDs) or acetaminophen.
Adult dose for acute painful musculoskeletal spasms (8)
Safety and effectiveness in pediatric patients below 15 years old have not been established (8).
Renal, hepatic and geriatric adjustments
Renal: no dosage adjustment needed in mild to severely altered kidney function, but use with caution due to limited safety and efficacy data (8).