Albuterol

- 5 mg/ml inhalation solution vials (nebulization).

- 90 and 100 ug/spray, aerosol metered (oral inhalation).

Executive Summary

(February 7, 2024)

 

Albuterol is a short-acting adrenergic β-2 receptor agonist (SABA). It is a fundamental treatment for bronchoconstriction crises typically caused by acute bronchitis, acute asthmatic exacerbations, and acutely decompensated COPD patients (20, 23).


Adult dose for moderate to severe acute bronchoconstriction

Adult dose

Adult dose for moderate to severe acute bronchoconstriction (6, 12, 20)


Comments


Adult dose for moderate to severe hyperkalemia (4, 12)

10-20 mg nebulized in 10 minutes . 


Comment:

Indications

Aerosol metered versus nebulized administration

Background


Clinical considerations

Asthma and COPD exacerbation: albuterol role

Overview


Severe acute asthmatic exacerbation


Severe acute COPD exacerbation

Hyperkalemia and albuterol

High doses of albuterol can lower potassium serum concentration by 0.5-2 mEq/L (13, 10).


Severe hyperkalemia significance and management overview


Clinical manifestations and ECG changes in hyperkalemia


Albuterol role in hyperkalemia

Cautions




Contraindications
Albuterol hypersensitivity. No other contraindications have been described. 


Adverse effects


Major drug interactions (22).


Therapeutic ceiling? overdose and lethal dose in animal studies (22) 

Pregnancy and lactation

Pregnancy risk classification


Lactation (7, 19)

References

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EMDrugs Team